Madaschi 2010.

Methods	Randomised controlled trial of fertility patients in Brazil
Participants	416 patients stratified according to age and then randomised to either acupuncture group (n = 208) or control with no acupuncture (n = 208)
Interventions	Needle acupuncture 25 minutes before and after embryo transfer versus no acupuncture control. Intervention performed by the same practitioner in all cases There was no statistically significant difference between the two groups for demographic characteristics. The average age (± SD) in the acupuncture group was 35.3 (± 4.7) compared to 34.6 (± 4.6) in the control group (p = 0.103). The average BMI in the acupuncture group was 22.4 (± 3.8) compared to 22.4 (± 2.9) in the control group (P = 0.951) The main causes of subfertility were ovarian disorders and male factor with no statistical significance between both groups for any cause of subfertility
Outcomes	Pregnancy rate, implantation rate, abortion rate and live birth rate
Assisted conception protocols	Standard, long protocol GnRH down‐regulation and the follicle stimulating hormone (FSH) or human menopausal gonadotrophin (hMG)
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	‘patients were randomized before the beginning of the ovarian stimulation according to computer generated randomized numbers ‘
Allocation concealment (selection bias)	Unclear risk	method of allocation concealment not reported
Blinding (performance bias and detection bias) All outcomes	High risk	Control group had no treatment. It was not stated if the clinicians or the assessors of the study were blinded.
Incomplete outcome data (attrition bias) All outcomes	Low risk	416 participants were randomized; no drop out noted.
Selective reporting (reporting bias)	Unclear risk	LBR not a prestated outcome.
Other bias	Low risk	None