Stener‐Victorin 1999.
Methods | Randomised controlled trial, conducted in Sweden | |
Participants | 150 women undergoing IVF and ET were randomised to receive either electro‐acupuncture and a paracervical block or alfentanil analgesia and a paracervical block. The mean ages (range) of the study and control groups were 33.3 years (25 to 42) and 34.4 years (25 to 46). There was no difference in the two groups in terms of the cause of subfertility and the number of previous cycles. |
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Interventions | Acupuncture was performed at least 30 min before oocyte aspiration and PCB was placed at the start of the procedure and terminated directly after oocyte aspiration | |
Outcomes | VAS, level of stress, implantation and pregnancy rates | |
Assisted conception protocols | Protocol breakdown not provided | |
Notes | Study designed to assess effectiveness of acupuncture as an analgesic | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | "Each centre randomized its patients using sealed, unlabelled envelopes" ‐ no further details |
Allocation concealment (selection bias) | Unclear risk | ‘sealed unlabelled envelope’ |
Blinding (performance bias and detection bias) All outcomes | High risk | Control group had traditional analgesia and t (Alfentanil + para cervical block) therefore blinding nor possible for clinicians or participants. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | 150 women were randomized. 1 drop out. |
Selective reporting (reporting bias) | Unclear risk | LBR data not reported. |
Other bias | Unclear risk | "There is a possible bias in the study in that some of the women in the EA group were administered additional alfentanil during oocyte aspiration." |