Westergaard 2006.
Methods | Randomised controlled trial with patients from private clinic in Denmark | |
Participants | 273 women randomised: 87 allocated to no acupuncture and 95 to acupuncture on ET day only; 91 to acupuncture on ET and ET+2 days; 27 excluded, The average ages of the three groups of women were: 37 years (27 to 45) in the control (n = 87) group, 37 years (24 to 45) in the group who had acupuncture on the day of ET (n = 95), and 37 years (27 to 45) for those with repeated acupuncture (ET + 2) (n = 91). There was no difference in the BMI between the three groups and about 67% of women had one or more attempts of IVF in the three groups. The main causes of subfertility were described as male factor or unexplained |
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Interventions | Acupuncture was performed by specially trained nurses on patients undergoing ET on the day of ET, ET+2 and not on controls | |
Outcomes | Clinical pregnancy rate on ultrasound | |
Assisted conception protocols | Standard, long protocol GnRH down‐regulation and the follicle stimulating hormone (FSH) or human menopausal gonadotrophin (hMG) | |
Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Randomisation procedure handled by nurse not involved in study |
Allocation concealment (selection bias) | Unclear risk | ‘drawing of sealed envelope’ ‐ no further details reported |
Blinding (performance bias and detection bias) All outcomes | High risk | Control group had paracervical block, so blinding of the participants and personnel not possible. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | 300 participants randomized. 27 dropped out leaving 273 participants for analysis. |
Selective reporting (reporting bias) | Unclear risk | LBR data not prestated outcome. |
Other bias | Low risk | none |