Table 4.

Taxa importance coincidence between the shotgun and 16S models: agreement and Kendall’s tau. Kendall rank correlation coefficient is computed considering all shared taxa in shotgun and 16S models. Agreement refers to the coincident taxa of the microbial signature shown in Fig. 8 (top-50 species), additional figures S5 (top 20 genera) and S6 (top 10 families). p-values < 0.05 are in bold

	Models	Agreement (top importances)	Kendall’s tau
			Kendall’s tau (95%CI)	p-value
Species	RF	22–36%	0.22 (0.05, 0.38)	4e-3
	SVM	18–36%	0.27 (0.13, 0.40)	5e-4
Genus	RF	30%	0.28 (0.14, 0.42)	4e-4
	SVM	20%	0.31 (0.17, 0.45)	1e-4
Family	RF	30%	0.30 (0.03,0.57)	0.01
	SVM	30%	0.31 (0.11, 0.51)	0.01