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. 2024 Jul 29;55:94. doi: 10.1186/s13567-024-01350-6

Table 1.

Timing of euthanasia and clinical signs

Animal Time of euthanasia (mpi) Reason for euthanasia Clinical signs or disease prior to euthanasia
90530 17 Intercurrent disease Lethargy, clinical hypocalcemia
90542 31 Intercurrent disease Degenerative joint disease
90501 42 Study endpoint Spontaneous smacking, reduced menace response
90506 42 Study endpoint Abnormal mental status, spontaneous smacking, reduced menace response, positive scratch test, abnormal gait
90507 42 Study endpoint Reduced menace response
90525 42 Study endpoint Spontaneous smacking, teeth grinding, reduced menace response, positive scratch test, abnormal gait

mpi months post-inoculation.