Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Genome designs to prevent insertions of partial genomes without transcriptional termination signal. The risk of insertional mutagenesis can be reduced by inverting the genome of self-complementary AAVs with promoter to the mTR (A) or deleting the promoter-proximal D-sequence from single-stranded AAVs (B).
