Figure 7.

Lung histology. Lung sections of hamsters were infected IN with 10⁴ PFU per 100 μl SARS-CoV-2 and euthanized at day 7 post-infection. Animals had been untreated prior to infection (PBS) or treated with 2 mg/kg H6 IN 24 or 2 h pre-infection (H6 24 h pre and H6 2 h pre) or 24 h post-infection (H6 24 h post) or B5-5 24 h or 2 h pre-infection (B5-5 2 h pre and B5-5 24 h pre). In the untreated animal (PBS), the lung parenchyma exhibits large, consolidated areas (arrows), whereas in treated animals there are only a few small areas of consolidation (arrows). HE stain, bars = 10 µm.