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Inhibition (IC50) of ACE-2 binding to SARS-CoV-2 Omicron spike protein variants by H6 trimeric nanobodies measured by electrochemiluminescence in MULTISPOT plates (Meso Scale Diagnostics).
| variant | BQ.1 | BQ.1.1 | XBB.1 | BA.2.75 | BA.2.75.2 | BF.7 | BA.4.6 |
|---|---|---|---|---|---|---|---|
| IC50 (nM) | 2.9 | 3 | 2.2 | 6.7 | 2.3 | 2.1 | 2.2 |
