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. 2024 Jul 29;19(7):e0307968. doi: 10.1371/journal.pone.0307968

Table 2. Resistance to serum killing among E. coli bloodstream infection isolates, stratified by multilocus sequence type (ST).

A serum bactericidal assay was performed on each E. coli isolate, and survival was determined by number of colonies in the serum-treated sample (either 25% or 50% serum) divided by the number of colonies in the negative serum control. The mean survival and range of survival values for each E. coli ST with ≥5 isolates in our study population are shown here. P-values were calculated with t-tests (e.g., proportion of surviving bacteria in ST12 relative to non-ST12 isolates). P-values ≤0.05 are in bold.

25% serum 50% serum
ST # isolates Mean proportion surviving Range of proportion surviving P-value Mean proportion surviving Range of proportion surviving P-value
12 7 0.72 0.65–0.90 0.21 0.71 0.66–0.89 0.20
69 12 0.70 0.65–0.93 0.41 0.69 0.61–0.94 0.41
73 12 0.68 0.61–0.77 0.97 0.67 0.58–0.72 0.88
95 18 0.68 0.62–0.92 0.84 0.68 0.59–0.93 0.60
127 5 0.68 0.66–0.70 1.00 0.67 0.64–0.71 1.00
131 67 0.67 0.61–0.74 0.05 0.66 0.60–0.73 0.05
393 10 0.66 0.57–0.76 0.17 0.66 0.60–0.74 0.41
405 6 0.67 0.64–0.70 0.29 0.66 0.62–0.68 0.50