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. 2024 Jul 29;19(7):e0307922. doi: 10.1371/journal.pone.0307922

Fig 5. Immunoblotting FOXO1 and insulin receptors.

Fig 5

FOXO1 was significantly increased in the sitagliptin non-ischemic group (SIT-N) compared to the control non-ischemic (CON-N) myocardium. pFOXO1 was significantly decreased in the sitagliptin ischemic group (SIT-I) compared to SIT-N. IRS-1 was significantly increased in the SIT-I myocardium compared to the control ischemic group (CON-I). There was no significant change in pIRS-1, pIRS-1 to IRS-1 ratio, or the pFOXO1 to FOXO1 ratio. Data points are mean fold change after normalization to average control. *<0.05, **p<0.01,***p<0.001.