Skip to main content
. 2024 Jul 29;19(7):e0307922. doi: 10.1371/journal.pone.0307922

Table 1. Fibrosis markers.

Table shows fibrosis markers. Data points are mean fold change after normalization to average control. Data is shown as mean and standard deviation (SD). Significant p-values (p<0.05) are highlighted in bold.

  SIT (Mean ± SD) p
Jak2 0.60 ± 0.10 0.006
pSTAT 0.37 ± 0.15 0.43
STAT 1.33 ± 0.23 0.046
pSTAT Ratio 3.62 ± 1.22 0.004
Connexin 0.91 ± 0.06 0.45
Alpha-Actinin 0.81 ± 0.13 0.02
Vimentin 0.96 ± 0.24 0.83
Filamin A 0.96 ± 0.12 0.17
TGF-Beta 2.54 ± 0.65 0.03
TGF-BR 0.74 ±0.26 0.27
pSMAD 2/3 0.51 ± 0.12 0.04
SMAD 2/3 0.73 ± 0.08 0.01
pSMAD Ratio 0.67 ± 0.13 0.15
pmTOR 0.75 ± 0.14 0.43
mTOR 1.01 ± 0.21 0.98
pMTOR Ratio 0.70 ± 0.06 0.01
TIMP 2 0.89 ± 0.32 0.45
MMP-13 1.93 ± 0.26 0.001