Table 2.

Thiopurine S-methyltransferase and Nudix hydrolase genotype frequencies and association of genotypes with leukopenia in the study population

Genotype	Cases (n=15), n (%)	Controls (n=14), n (%)	P	OR (95% CI)
TPMT *1/*1	12 (80)	14 (100)	0.22	0.12 (0.006–2.6)
TPMT *1/*3C	3 (20)	0
NUDT15 *1/*1	11 (73.3)	12 (85.7)	0.65	0.46 (0.07–3)
NUDT15 *1/*3	4 (26.7)	2 (14.3)

Values are expressed as n (%), P value computed using Fisher’s exact test, calculated with Haldane-Anscombe correction as some cells had zero value. TPMT=Thiopurine S-methyltransferase, NUDT15=Nudix hydrolase, OR=Odds ratio, CI=Confidence interval