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. 2023 Dec 13;131(1):106–123. doi: 10.1152/jn.00086.2023

Figure 4.

Figure 4.

Hypothetical examples of homotopic effects, heterotopic effects, and no effect of cooling M1 for a stimulation site in area 1. The top illustration shows the location of two cooling chips in M1, one in the forelimb representation and one in the face representation, with the body parts color coded at right. A: illustrates a homotopic effect in which cooling the forelimb representation in M1 (medial cooling chip, outlined in black) abolishes a forelimb movement evoked by ICMS in area 1. B: illustrates a heterotopic effect in which cooling the face representation in M1 abolishes an area 1 ICMS-evoked forelimb movement. C: illustrates an alternative outcome to that shown in B. Here, there is no effect on an area 1-ICMS-evoked forelimb movement when the face representation in M1 is cooled. For conventions, see previous figures. ICMS, intracortical microstimulation.