Table 1.
Demographics of the POP01 external evaluation data set. PNA: Postnatal age
| Variable | Median (Range) or N (%) | |||
|---|---|---|---|---|
| PNA <2 years | PNA ≥ 2 to ≤ 8 years | PNA >8 years | Total | |
| N | 41 | 26 | 35 | 102 |
| Postnatal age (years) | 0.35 (0.01–1.86) | 4.56 (2.07–7.93) | 14.4 (8.34–19.9) | 3.61 (0.01–19.9) |
| Postmenstrual agea (weeks) | 58.3 (37.7–137) | 277 (148–454) | 793 (473–1080) | 226 (37.7–1080) |
| Body weight (kg) | 5.70 (2.66–12.8) | 17.27 (9.20–33.0) | 55.0 (24.0–112) | 16.3 (2.66–112) |
| Body mass index (kg/m2) | 15.7 (10.9–25.1) | 15.9 (13.5–25.4) | 23.4 (13.8–38.6) | 17.8 (10.9–38.6) |
| Body mass index percentile | NAb | 57.9 (4.68–99.2) | 88.2 (0.05–99.6) | 78.5 (0.05–99.6) |
| Female | 20 (48.8) | 12 (46.2) | 15 (42.9) | 47 (46.1) |
| Serum Creatinine (mg/dL) | 0.3 (0.1–1.0) | 0.44 (0.19–2.30) | 0.60 (0.1–1.95) | 0.41 (0.1–2.30) |
| Serum Albumin (g/dL) | 2.8 (2.0–4.1) | 3.2 (2.0–5.3) | 2.8 (1.5–4.6) | 2.9 (1.5–5.3) |
| Race | ||||
| White | 31 (75.6) | 20 (76.9) | 25 (71.4) | 76 (74.5) |
| Black or African American | 7 (17.1) | 2 (7.7) | 7 (20) | 16 (15.7) |
| Asian | 1 (2.4) | 1 (3.8) | 1 (2.9) | 3 (2.9) |
| Native American | 0 (0) | 0 (0) | 1 (2.9) | 1 (1.0) |
| Unknown or not reportedc | 2 (4.8) | 3 (11.5) | 1 (2.9) | 6 (5.8) |
| Ethnicity | ||||
| Hispanic or Latino | 5 (12.2) | 2 (7.7) | 1 (2.9) | 8 (7.8) |
| Not Hispanic or Latino | 36 (87.8) | 24 (92.3) | 34 (97.1) | 94 (92.2) |
| Obese Statusd | ||||
| With Obesity | NAb | 6 (23.1) | 11 (31.4) | 17 (16.7) |
| Had Surgerye | ||||
| Yes | 10 (24.4) | 5 (19.2) | 7 (20.0) | 22 (21.6) |
a
Postmenstrual age was calculated as PNA + 40 weeks when GA was missing
b
Body mass index percentile is not available for patients <2 years of age
c
Includes individuals listed as ‘mixed race’
d
Obesity defined by BMI > 95th percentile for age and sex (body mass index percentile > 95)
e
Reported as surgery occurring within 24h prior to the first dose of dexmedetomidine