Table 3.

RORs and 95% CI for each antipsychotic (ROR > 1 indicates an increased DRESS syndrome reporting associated with antipsychotics); carbamazepine was considered as a comparator

Medication	n DRESS	n ADR	ROR	Lower 95% ROR	Higher 95% ROR	CI	Lower 95% CI	Higher 95% CI
Antipsychotics	1356	728,105	0.13	0.12	0.14	−0.56	−0.61	−0.52
Typical	175	101,520	0.04	0.04	0.05	−3.25	−3.50	−3.07
Atypical	1224	595,520	0.05	0.05	0.06	−1.5	−1.59	−1.43
Clozapine	800	184,094	0.11	0.10	0.12	−1.65	−1.77	−1.57
Olanzapine	152	71,859	0.05	0.05	0.06	−3.22	−3.49	−3.03
Quetiapine	134	87,822	0.04	0.03	0.05	−3.53	−3.82	−3.32
Risperidone	89	114,334	0.02	0.02	0.02	−4.25	−4.60	−4.00
Aripiprazole	61	70,082	0.02	0.02	0.03	−4.46	−4.88	−4.15
Haloperidol	57	35,870	0.04	0.03	0.05	−4.00	−4.44	−3.68
Chlorpromazine	37	12,636	0.07	0.05	0.10	−3.45	−4.00	−3.06
Cyamemazine	23	5188	0.11	0.08	0.17	−2.97	−3.67	−2.48
Lurasidone	23	13,145	0.04	0.03	0.07	−4.17	−4.87	−3.68
Ziprasidone	23	14,911	0.04	0.03	0.06	−4.32	−5.02	−3.83
Amisulpride	16	7725	0.05	0.03	0.09	−4.01	−4.85	−3.43
Levomepromazine	13	5368	0.06	0.04	0.11	−3.81	−4.75	−3.17
Paliperidone	12	47,633	0.01	0.00	0.01	−6.43	−7.41	−5.76
Loxapine	11	3775	0.07	0.04	0.13	−3.57	−4.59	−2.88
Zuclopenthixol	11	4359	0.06	0.04	0.12	−3.76	−4.78	−3.07
Sulpiride	7	4861	0.04	0.02	0.08	−4.53	−5.83	−3.68
Tiapride	7	1922	0.09	0.04	0.20	−3.25	−4.55	−2.40
Perphenazine	6	3323	0.05	0.02	0.10	−4.21	−5.63	−3.30
Droperidol	5	2197	0.06	0.02	0.14	−3.88	−5.44	−2.90

ADR adverse drug reaction, CI confidence interval, DRESS drug reaction with eosinophilia and systemic symptoms, n number, ROR reporting odds ratio