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. 2024 May 9;47(8):745–757. doi: 10.1007/s40264-024-01431-7
Clozapine, chlorpromazine, and cyamemazine are associated with disproportionate reporting of drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome compared to other medications.
Serious DRESS cases were more often associated with concurrent use of multiple antipsychotics compared to non-serious ones, while this difference was not found regarding oral/long-acting injectable formulations.
Fatal cases for antipsychotic-related DRESS syndrome stood at 10.7% (164 cases).