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. 2024 Jul 29;14:17459. doi: 10.1038/s41598-024-68338-2

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© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Forest plots showing (a) positive predictive values (PPV) and (b) negative predictive values (NPV) of Gynecologic Cancer Intergroup (GCIG) CA125 criteria response predicting RECIST response in patient subgroups. n/N refers to the number of (CA125 response and RECIST response)/([CA125 response and RECIST response] + [CA125 response and RECIST non-response]) for PPV and (CA125 non-response and RECIST non-response)/([CA125 non-response and RECIST non-response] + [CA125 non-response and RECIST response]) for NPV. Forest plots showing (c) PPV and (d) NPV of GCIG CA125 criteria disease progression (PD) predicting RECIST PD in patient subgroups. n/N refers to the number of (CA125 PD and RECIST PD)/([CA125 PD and RECIST PD] + [CA125 PD and RECIST non-PD]) for PPV and (CA125 non-PD and RECIST non-PD)/([CA125 non-PD and RECIST non-PD] + [CA125 non-PD and RECIST PD]) for NPV.