Table 1.
Female sex, N (%) | 81 (100%) |
Age in years, median (IQR) | 63.2 (56.2, 68.4) |
Prior number of systemic therapies, median (IQR) | 4 (3, 6) |
Prior therapy exposure | |
Prior platinum-based therapy | 81 (100%) |
Prior PARP inhibitor | 47 (58.0%) |
ECOG performance status at start of trial, N (%) | |
0 | 15 (18.5%) |
1 | 66 (81.5%) |
FIGO stage at diagnosis, N (%) | |
I or II | 3 (3.70%) |
III | 60 (74.1%) |
IV | 18 (22.2%) |
Race, N (%) | |
African American/Black | 5 (6.17%) |
Asian | 2 (2.47%) |
White | 73 (90.1%) |
Unknown | 1 (1.23%) |
BRCA mutation status, N (%) | |
BRCA-mutant | 18 (22.2%) |
BRCA-wildtype | 63 (77.8%) |
Platinum sensitivity, N (%) | |
Platinum-sensitive | 13 (16.0%) |
Platinum-resistant | 67 (82.7%) |
Platinum-refractory | 1 (1.23%) |
Baseline CA125, median (IQR) | 349 (107, 1500)* |
Baseline CA125, N (%) | |
Normal (0–16.3 units/mL) | 3 (3.70%) |
Abnormal (> 16.3 units/mL) | 78 (96.3%) |
ECOG Eastern Cooperative Oncology Group, FIGO International Federation of Gynecology and Obstetrics, IQR interquartile range, RECIST response evaluation criteria in solid tumors. *Values > 1500 units/mL calculated as 1500 units/mL.