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. 2024 Jul 29;14:17459. doi: 10.1038/s41598-024-68338-2

Table 3.

Predictive value of GCIG CA125 PD/no-PD.

RECIST PD No RECIST PD Total
GCIG CA125 PD 24 19 43

PPV: 56%

95% CI: 40 to 71

No GCIG CA125 PD 18 9 27

NPV: 33%

95% CI: 17 to 54

Total 42 28 70

Positive predictive value (PPV) and negative predictive value (NPV) of GCIG CA125 disease progression (PD) criteria to predict RECIST PD within one cycle of CA125 PD. PPV: probability of patients with CA125 PD also had RECIST PD, NPV: probability that those without CA125 PD also did not have RECIST PD.

CA125 cancer antigen 125, CI confidence interval, GCIG Gynecologic Cancer Intergroup, NPV negative predictive value, PD disease progression, PPV positive predictive value, RECIST response evaluation criteria in solid tumors.

Significant values are in bold.