Table 3.
RECIST PD | No RECIST PD | Total | ||
---|---|---|---|---|
GCIG CA125 PD | 24 | 19 | 43 |
PPV: 56% 95% CI: 40 to 71 |
No GCIG CA125 PD | 18 | 9 | 27 |
NPV: 33% 95% CI: 17 to 54 |
Total | 42 | 28 | 70 |
Positive predictive value (PPV) and negative predictive value (NPV) of GCIG CA125 disease progression (PD) criteria to predict RECIST PD within one cycle of CA125 PD. PPV: probability of patients with CA125 PD also had RECIST PD, NPV: probability that those without CA125 PD also did not have RECIST PD.
CA125 cancer antigen 125, CI confidence interval, GCIG Gynecologic Cancer Intergroup, NPV negative predictive value, PD disease progression, PPV positive predictive value, RECIST response evaluation criteria in solid tumors.
Significant values are in bold.