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. 2024 Apr 1;5(7):100890. doi: 10.1016/j.xplc.2024.100890

Figure 1.

Figure 1

TRB4 and TRB5 bind to telomere repeats and belong to a separate TRB clade that is conserved in gymnosperms and angiosperms

(A) Volcano plot showing enrichment of the five TRB proteins (red dots) in the telomere repeat pull-down relative to scrambled control sequences. Mean enrichment values from four independent experiments are indicated.

(B) Presence or absence of orthologs of the Arabidopsis TRB proteins in different plant species spanning the evolutionary history of land plants. TRB orthologs were detected in the liverwort Marchantia, and orthologs of TRB1–3 (black) and TRB4–5 (gray) are present in gymnosperms, basal angiosperms, and mono- and dicotyledons.

(C) Unrooted maximum-likelihood phylogenetic tree of 87 TRB orthologs from 15 Brassicaceae species.

(D) Presentation of nine motifs in the A. thaliana TRB proteins predicted with MEME from an alignment of TRB orthologs from 15 Brassicaceae species. Sequences of consensus motifs are indicated. Distinct motifs adjacent to the MYB/SANT domain and different coiled-coil domains in the C termini differentiate clade I from clade II TRB proteins.