TABLE 3.

Comparative analysis of relative miRNA expression between the control group and patients with atrial TR and ventricular TR

miRNA	Control	Atrial TR	Ventricular TR
hsa‐miR‐409‐3p	1.00 (0.72–1.37)	1.22 (0.86–1.72)	1.35 (1.01–1.81)
hsa‐miR‐375	1.00 (0.73–1.36)	1.12 (0.80–1.57)	0.95 (0.70–1.29)
hsa‐miR‐222‐3p	1.00 (0.90–1.11)	1.08 (0.96–1.21)	1.13 (1.00–1.28)
hsa‐miR‐15a‐5p	1.00 (0.88–1.13)	1.07 (0.89–1.28)	1.21 (1.05–1.39) *
hsa‐miR‐29b‐3p	1.00 (0.92–1.09)	0.83 (0.71–0.98) *	0.97 (0.85–1.11)
hsa‐miR‐152‐3p	1.00 (0.90–1.11)	0.58 (0.49–0.67) ****	0.66 (0.59–0.73) ****
hsa‐miR‐30e‐5p	1.00 (0.83–1.20)	0.43 (0.36–0.50) ****	0.48 (0.42–0.54) ****
hsa‐miR‐186‐5p	1.00 (0.89–1.12)	0.08 (0.03–0.16) ****	0.13 (0.07–0.26) ****
hsa‐miR‐101‐3p	1.00 (0.89–1.12)	0.94 (0.77–1.13)	1.14 (0.92–1.42)
hsa‐miR‐126‐5p	1.00 (0.89–1.12)	0.82 (0.75–0.97) *	0.95 (0.83–1.09)
hsa‐miR‐92a‐3p	1.00 (0.86–1.16)	1.03 (0.84–1.27)	1.19 (1.02–1.38)
hsa‐miR‐363‐3p	1.00 (0.84–1.19)	1.09 (0.85–1.39)	1.23 (1.02–1.48)
hsa‐miR‐148a‐3p	1.00 (0.89–1.12)	0.84 (0.72–0.98) *	0.92 (0.80–1.05)
hsa‐miR‐324‐3p	1.00 (0.90–1.11)	0.99 (0.86–1.13) #	1.17 (1.04–1.31) * , #
hsa‐miR‐22‐3p	1.00 (0.87–1.14)	1.05 (0.88–1.25)	1.24 (1.09–1.42) *
hsa‐miR‐29c‐3p	1.00 (0.89–1.13)	0.90 (0.78–1.03) #	1.03 (0.92–1.17) #

Data represented as geometric mean (95% confidence interval). The relative expression of the miRNAs analysed by qPCR is expressed as the normalized value of 2^−ΔΔCt.

TR, tricuspid regurgitation.

^* P‐value ≤0.05, compared with the control group.

^**** P‐value ≤0.0001, compared with the control group.

^# P‐value ≤0.05, comparing atrial TR versus ventricular TR patients.