Table 3. Overall Unadjusted and Adjusted Associations Between Dietary Exposure and GrimAge2.

Dietary exposure	β (95% CI)
	Unadjusted (n = 342)a	Adjusted (n = 325)b
Alternate Mediterranean diet score	−0.62 (−0.91 to −0.34)c	−0.41 (−0.69 to −0.13)c
Alternate Healthy Eating Index –2010 score	−0.10 (−0.13 to −0.06)c	−0.05 (−0.08 to −0.01)c
Epigenetic Nutrient Index score	−0.19 (−0.29 to −0.08)c	−0.17 (−0.29 to −0.06)c
Added sugar, g	0.02 (0.01 to 0.04)c	0.02 (0.01 to 0.04)c

^a Adjusted for factors identified through epigenetic clock best practices and expert recommendations: current age, sample batch, and naive CD8 and CD8pCD28nCD45Ran memory and effector T-cell counts.

^b Adjusted for current age, sample batch, naive CD8 and CD8pCD28nCD45Ran memory and effector T-cell counts, race (Black or White), ever diagnosis of a chronic condition, current medication use, baseline (age 9-10 years) household income, baseline (age 9-10 years) highest parental educational attainment, number of parents in household at baseline (age 9-10 years), number of siblings at baseline (age 9-10 years), body mass index at midlife, mean total kilocalories, and ever smoking status assessed at midlife (yes or no). As a complete cases analysis approach was taken, adjusted vs unadjusted analyses differed by n = 17 women with missing baseline household income data.

^c Statistically significant result (P < .05).