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. 2024 Jul 29;7(7):e2422749. doi: 10.1001/jamanetworkopen.2024.22749

Table 4. Overall Adjusted Associations for Diet Quality Scores and Added Sugar With GrimAge2 Where Dietary Exposures Are Combined Among 325 Participants.

Dietary exposure modela Adjusted β (95% CI)b
Model 1: aMED and added sugar
aMED score −0.29 (−0.58 to −0.00)c
Added sugar, g 0.02 (0.00 to 0.03)c
Model 2: AHEI-2010 and added sugar
AHEI score −0.03 (−0.07 to 0.01)
Added sugar, g 0.02 (0.00 to 0.03)c
Model 3: ENI and added sugar
ENI score −0.12 (−0.25 to 0.01)
Added sugar, g 0.02 (0.00 to 0.03)c

Abbreviations: AHEI-2010, Alternate Healthy Eating Index 2010; aMED, Alternate Mediterranean Diet; ENI, Epigenetic Nutrient Index.

a

Each dietary exposure model consisted of 1 diet quality score measure (aMED, AHEI-2010, or ENI) (1) plus added sugar (1).

b

Adjusted for current age, sample batch, naive CD8 and CD8pCD28nCD45Ran memory and effector T-cell counts, race (Black or White), ever diagnosis of a chronic condition, current medication use, baseline (age 9-10 years) household income, baseline (age 9-10 years) highest parental educational attainment, number of parents in household at baseline (age 9-10 years), number of siblings at baseline (age 9-10 years), body mass index at midlife, mean total kilocalories, and ever smoking status assessed at midlife (yes or no).

c

Statistically significant result (P < .05).