Table 1.
Aggregate baseline characteristics of patients in the (1) protein biomarkers of platelet activation (n = 1399) and (2) platelet function testing (n = 443) cohorts
| Variable | Protein biomarkers cohort (n = 1399) | Platelet function testing cohort (n=443) |
|---|---|---|
| Age (years), median (IQR) | 63 (55, 69) | 63 (56, 70) |
| Female | 27.1% (379) | 22.6% (100) |
| White race | 95.1% (1330) | 93.9% (416) |
| BMI, median (IQR) | 30.1 (27.0, 33.7) | 29.7 (26.8, 33.2) |
| Diabetes mellitus | 30.4% (425) | 28.5% (126) |
| Hypertension | 74.0% (1033) | 69.3% (307) |
| Current cigarette smoker or within past year | 26.0% (362) | 23.4% (103) |
| Prior stroke/TIA | 4.4% (61) | 4.3% (19) |
| Heart failure | 4.3% (60) | 3.6% (16) |
| Peripheral arterial disease | 6.5% (90) | 4.5% (20) |
| Previous percutaneous coronary intervention (PCI) | 32.9% (457) | 28.6% (126) |
| Coronary artery bypass graft (CABG) | 13.7% (191) | 12.0% (53) |
| Previous myocardial infarction (MI) | 21.4% (292) | 19.2% (84) |
| Indication for index procedure | ||
| STEMI | 11.7% (163) | 11.3% (50) |
| NSTEMI | 16.0% (224) | 15.3% (68) |
| Unstable angina | 14.9% (209) | 13.3% (59) |
| Stable angina | 35.4% (495) | 36.3% (161) |
| Other | 22.0% (308) | 23.7% (105) |
| Type of stent at index procedure | ||
| DES only | 86.2% (1206) | 85.6% (379) |
| BMS only | 13.8% (193) | 14.4% (64) |
BMI body-mass index, BMS bare metal stent, DES drug-eluting stent, IQR interquartile range, NSTEMI non-ST-segment elevation myocardial infarction, STEMI ST-segment elevation myocardial infarction, TIA transient ischemic attack