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. Author manuscript; available in PMC: 2024 Jul 30.
Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Jun 16;1867(9):159195. doi: 10.1016/j.bbalip.2022.159195

Figure 1. Intestinal SCD1 is induced by feeding a high-sucrose diet and is enriched in distal small intestine.

Figure 1.

(A) Generation of MUFA products by cellular SCD1 activity; SCD1 products are in red, and elongation products are in gray. (B-C) Scd1 expression in chow-fed or fasted and sucrose-refed animals in proximal, middle, and distal small intestine and colon; n=5–8. Averages ± SEM, bars with different letters are significantly different from each other. (D,E) SCD1 protein expression in the proximal, middle, and distal intestine and colon of chow-fed and sucrose-fed mice. Each lane contains protein pooled from 3 animals; *, p<0.05 vs. proximal (F) Immunohistochemical staining for SCD1 in intestines; images representative of three animals each; scale bar represents 25 μM. SCD1, Stearoyl-CoA Desaturase 1, β-Actin, Beta-Actin, GAPDH, glyceraldehyde 3-phosphate dehydrogenase.