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. Author manuscript; available in PMC: 2024 Jul 30.
Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Jun 16;1867(9):159195. doi: 10.1016/j.bbalip.2022.159195

Figure 3. Intestinal structure is slightly altered, but gut motility and fat absorption are intact in iKO mice.

Figure 3.

(A,B) Lengths of small intestine and colon were slightly increased in iKO mice; n=8–12. (C) H&E staining of Swiss-rolled intestine segments do not show any apparent pathological changes in iKO mice. Images are representative of 3 chow-fed mice, and images were taken throughout length of intestine; scale bar represents 25 μM. (D-F) Villus lengths were not alterd, but villus widths and crypt depths were slightly reduced in iKO mice; data represent 50–60 villi counted from 3 chow-fed mice. (G,H) Fecal fat content and gut transit time were not altered in chow-fed iKO mice; n=5–6. Averages ± SEM. *p<0.05 vs fl.