(A-E) Total content of plasma triacylglycerols (TAG), cholesterol esters (CE), diacylglycerols (DAG), free fatty acids (FFA), and phospholipids (PL) were determined by TLC-GC-MS. (F) Plasma free cholesterol was colorimetrically determined. (G, H) Desaturation ratios for 14–18 carbon chain lipid species were calculated for each lipid fraction from chow-fed and sucrose-fed mice. Red text denotes desaturation ratios that were significantly reduced, and blue text denotes desaturation ratios that were significantly increased in iKO mice, relative to diet-matched fl/fl controls. n=6. Averages ± SEM. *p<0.05 vs fl/fl.