FIGURE 1.

Study design. ^aParticipants were discharged after the final blood sampling, depending on what study drugs they received. The timing of blood sampling after the final morning dose of 7‐day repeated administration was 24 h for pravastatin, simvastatin, and fluvastatin; 24 and 36 h for pitavastatin and atorvastatin; and 24, 36, 48, and 72 h for rosuvastatin. That for pemafibrate was 24 h in the studies with pitavastatin, atorvastatin, and rosuvastatin and 24, 36, and 48 h in the studies with pravastatin, simvastatin, and fluvastatin. ^bParticipants received study drugs for 7 days from the morning to the second day of hospitalization. They received one of three treatments, pemafibrate alone, statin alone, and the combination of the two, during each of three hospitalization periods in the order of allocated one of the six sequence groups. ^cWashout period was the same within the same individual.