Table 2. Distribution of homozygous and heterozygous values of c.433 A>G p.R145G (rs880633) polymorphism between severe and non-severe preeclampsia group in preeclampsia and control group.
| Control (n=40) | Preeclampsia | p1 | p2 | OR 95%CI | p3 | p4 | |||
|---|---|---|---|---|---|---|---|---|---|
| Non-severe (n=14) | Severe (n=21) | ||||||||
| No polymorphism | 8 (20.0%) | 6 (42.9%) | 8 (38.1%) | 0.026* | 0.058 | 0.37 (0.13–1.04) | 0.092 | 0.158 | |
| Polymorphism is present | 32 (80.0%) | 8 (57.1%) | 13 (61.9%) | ||||||
| Homozygous | 7 (17.5%) | 3 (21.4%) | 7 (33.3%) | ||||||
| Heterozygous | 25 (62.5%) | 5 (35.7%) | 6 (28.6%) | ||||||
Data are given as n (%). p1=control and preeclampsia group with no polymorphism, comparison of homozygous and heterozygous; p2=control and preeclampsia group with no polymorphism comparing polymorphism exists; p3=control, severe, and non-severe preeclampsia group without polymorphism, comparison of homozygous and heterozygous; p4=control, comparison of severe and non-severe preeclampsia group with no polymorphism with polymorphism exists.
*
p<0.05 was accepted as statistically significant.