Table 4.
Summary of ethics approvals and consent among patients.
| Study | Did you obtain ethics approval for this study? | Start date | End date | Type of informed consent obtained | Does the study include minors? | Was informed parental consent obtained for minors? | Was informed consent obtained for adults? | |
| Colombia: Diagnosis Cohort: Evaluation of the diagnostic accuracy and usefulness of rapid tests for early diagnosis of dengue | Yes | January 23, 2020 | June 1, 2020 | Written | Yes | Yes | Yes | |
| Colombia: Prognosis Cohort: Immune Mechanisms of Pathogenesis in Patients with Dengue Infection | Yes | March 18, 2019 | February 20, 2020 | Written | Yes | Yes | Yes | |
| Colombia: Piedecuesta’s household-based dynamic cohort. Identification of age groups to be prioritized for vaccination in a population of children and adolescents |
Yes | June 1, 2015 | December 30, 2018 | Written | Yes | Yes | Yes | |
| Colombia: AEDESa Cohorts | ||||||||
|
|
Identification of prognostic markers of severity in dengue | Yes. A copy of IRBb approval obtained in 2003 was requested. | April 1, 2003 | March 30, 2005 | Written | Yes | Yes | No |
|
|
Validation of a clinical definition for dengue and evaluation of its usefulness to identify early conditions associated with hospitalization | Yes. A copy of IRB approval obtained in 2005 was requested. | February 1, 2006 | April 30, 2008 | Written | Yes | Yes | N/Ac |
|
|
Colombian multicentric study | Yes | May 1, 2009 | May 30, 2011 | Written | Yes | Yes | N/A |
| CDY15: Efficacy and safety of a new tetravalent dengue vaccine in healthy children and adolescents aged 9 years to 16 years in Latin America | yes | Jun 15, 2011 | Feb 28, 2018 | Written | Yes | Yes | Yes | |
| PDCSd (Nicaragua) | Yes | August 31, 2004 | Ongoing | Informed consent, parental; verbal assent | Yes | Yes | Yes | |
| PDHSe (Nicaragua) | Yes | August 4, 2005 | Ongoing | Informed consent; verbal assent; written assent | Yes | Yes | Yes | |
| IDAMSf (Carabobo, Venezuela) | Yes | September 27, 2013 | November 14, 2016 | Written | Yes | Yes | Yes | |
| IDAMS (Rio de Janeiro, Brazil) | Yes | April 6, 2015 | May 9, 2016 | Written | Yes | Yes | Yes | |
| Cohort of Pregnant Women (Brazil) | Yes | September 1, 2015 | May 30, 2016 | Written | Yes | Yes | Yes | |
aAEDES: Abordando Áreas Endémicas del Dengue Para el Estudio de su Severidad.
bIRB: institutional review board.
cN/A: not applicable.
dPDCS: Pediatric Dengue Cohort Study.
ePDHS: Prospective Hospital-Based Study of Dengue Classification, Case Management, and Diagnosis.
fIDAMS: International Research Consortium on Dengue Risk Assessment, Management and Surveillance.