Extended Data Fig. 1. Designed peptide binder controls.
a, SEC binding assay showing that a fusion protein between GFP and 104 peptide binds to the C104 design on a S75 increase 10/300. b, Close-up view of the buried part of the C104 interface with Val6 shown in cyan sticks and spheres. Binder in gray and peptide in dark red. c, Biolayer interferometry trace of C104 binding to base peptide 104 and to a peptide with a V6R substitution. d, Interface close up view of C104 highlighting the hydrophobic-hydrophilic pattern of the peptide. Buried residues single letter amino acid identifiers are underlined.