TABLE 3.
Lipinski’s rule of five application data.
| Sample | MW | Relative amount (%) | Log p | H donor | H acceptor | Violation |
|---|---|---|---|---|---|---|
| Cinnamaldehyde | 132.16 | 62 | 2.48 | 0 | 1 | 0 |
| Eugenol | 164.20 | 85 | 2.10 | 1 | 2 | 0 |
| Linalool | 154.25 | 25 | 3.21 | 1 | 1 | 0 |
| Cineol | 154.24 | 40 | 2.72 | 0 | 1 | 0 |
MW (molecular weight<500 kDa); Log p(<5); H donor(H bond donor <5); H acceptor(H-bond acceptor(<10); Violations (No. of violations).