Table 1.
Characteristics of matched sepsis cases and controls
| Sepsis cases | Controls | Community-acquired sepsis cases | Hospital-acquired sepsis cases | |
|---|---|---|---|---|
| Total N | 119,529 | 703,237 | 108,317 | 11,212 |
| Age mean (SD) | ||||
| Mean | 80.6 (8.2) | 80.4 (8.1) | 80.6 (8.2) | 80.7 (8) |
| Sex N (%) | ||||
| Women | 60,743 (50.8%) | 361,564 (51.4%) | 55,144 (50.9%) | 5599 (49.9%) |
| Ethnicity N (%) | ||||
| Black | 1585 (1.3%) | 9255 (1.3%) | 1400 (1.3%) | 185 (1.7%) |
| Mixed | 242 (0.2%) | 1610 (0.2%) | 216 (0.2%) | 26 (0.2%) |
| Other | 873 (0.7%) | 6388 (0.9%) | 800 (0.7%) | 73 (0.7%) |
| South Asian | 2375 (2.0%) | 13,672 (1.9%) | 2152 (2.0%) | 223 (2.0%) |
| Unknown | 3816 (3.2%) | 65,559 (9.3%) | 3474 (3.2%) | 342 (3.1%) |
| White | 110,638 (92.6%) | 606,753 (86.3%) | 100,275 (92.6%) | 10,363 (92.4%) |
| Smoking history N (%) | ||||
| None | 23,080 (19.3%) | 132,489 (18.8%) | 20,903 (19.3%) | 2177 (19.4%) |
| Current | 35,229 (29.5%) | 166,651 (23.7%) | 31,921 (29.5%) | 3308 (29.5%) |
| Past | 16,511 (13.8%) | 84,117 (12%) | 15,003 (13.9%) | 1508 (13.4%) |
| Unknown | 44,709 (37.4%) | 319,980 (45.5%) | 40,490 (37.4%) | 4219 (37.6%) |
| Frailty N (%) | ||||
| None | 11,406 (9.5%) | 139,341 (19.8%) | 10,454 (9.7%) | 952 (8.5%) |
| Minor | 60,403 (50.5%) | 369,212 (52.5%) | 54,632 (50.4%) | 5771 (51.5%) |
| Moderate | 32,435 (27.1%) | 141,920 (20.2%) | 29,387 (27.1%) | 3048 (27.2%) |
| Severe | 15,285 (12.8%) | 52,764 (7.5%) | 13,844 (12.8%) | 1441 (12.9%) |
| Deprivation N (%) | ||||
| Not deprived | 25,693 (21.5%) | 174,986 (24.9%) | 23,356 (21.6%) | 2337 (20.8%) |
| Less deprived | 25,489 (21.3%) | 162,782 (23.1%) | 23,171 (21.4%) | 2318 (20.7%) |
| Moderately deprived | 24,045 (20.1%) | 144,077 (20.5%) | 21,813 (20.1%) | 2232 (19.9%) |
| More deprived | 22,798 (19.1%) | 121,906 (17.3%) | 20,642 (19.1%) | 2156 (19.2%) |
| Most deprived | 21,504 (18.0%) | 99,486 (14.1%) | 19,335 (17.9%) | 2169 (19.3%) |