Table 2.
A | B | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Variables | CL, n = 31 | 3 months post-COVID-19, n = 29 | 6 months post-COVID-19, n = 23 | 12 months post-COVID-19, n = 20 | P-value (COVID-19 vs CL) | 3 months post-COVID-19 w/o PE, n = 19 | 3 months post-COVID-19 with PE, n = 10 | 6 months post-COVID-19 w/o PE, n = 15 | 6 months post-COVID-19 with PE, n = 8 | 12 months post-COVID-19 w/o PE, n = 13 | 12 months post-COVID-19 with PE, n = 7 | P-value (COVID-19 with PE vs w/o PE) |
Appearance of ECFC colonies (%) | 15 (48.4%) | 24 (82.8%)** | 20 (87.0%)** | 17 (85.0%)** | P < 0.05 | 15 (79.0%) | 9 (90.0%) | 14 (93.3%) | 6 (75.0%) | 11 (84.6%) | 6 (85.7%) | ns |
Number of ECFC colonies | 1.23 ± 1.86 | 2.79 ± 2.41* | 2.78 ± 2.00* | 2.90 ± 2.61* | P < 0.05 | 2.47 ± 2.17 | 3.40 ± 2.84 | 2.73 ± 1.62 | 2.88 ± 2.70 | 2.62 ± 2.29 | 3.43 ± 2.26 | ns |
Time for ECFC to appear (days) | 14.3 ± 4.76 | 11.6 ± 4.73 | 10.8 ± 3.23 | 12.1 ± 4.10 | ns | 11.7 ± 3.81 | 11.4 ± 6.23 | 11.6 ± 3.25 | 8.67 ± 2.16 | 12.1 ± 4.89 | 12.0 ± 2.45 | ns |
CL healthy control, PE Pulmonary embolism, ECFC endothelial colony-forming cells
A. Cellular parameters of post-COVID-19 patients at different time points after overcoming COVID-19 (3, 6 and 12 months). Values expressed as mean ± SD. Ordinary one-way ANOVA followed by Tukey´s multiple comparisons test for parametric tests, Kruskal–Wallis test followed by Dunn’s multiple comparisons test for non-parametric tests and Chi squared test for categorical variables, *P < 0.05, **P < 0.01
B. Cellular parameters of 3,6 and 12-months post-COVID-19 patients, with or w/o pulmonary embolism (PE). Values expressed as mean ± SD. Unpaired t test for parametric tests, Mann–Whitney test for non-parametric tests and Chi squared test for categorical variables, P > 0.05