Figure 2.

Amino acid changes in the different domains of JN.1 in comparison with Wuhan-Hu-1, BA.2, and XBB omicron variants. (Red color indicates the unique mutations, the blue color indicates the dynamic mutations, the black color indicates random mutations and pale red indicates universal mutations). Footnotes: FP Fusion peptide, HR1/2 heptad repeat, NTD N-terminal domain, RBD receptor binding domain, SP signal peptide, SD spike subdomain, TM transmembrane domain. The aforementioned are the different motifs of the SARS-CoV-2 spike glycoprotein.