Table 1.

Unique and dynamic mutational pattern in spike protein among different lineages.

S. no	Comparison	Unique mutations (n)	Unique mutations	Dynamic mutations (n)	Dynamic mutations
1	JN.1 variants with Wuhan-Hu-1	22	T20L, P26Q, D53E, F55L, S60F, N81S, V83F, L84K, P85L, F86L, N87I, D88V, V90L, P174S, Q218L, A288S, V503A, P681R, M740I, S939F, V1104L, P1162L	3	P85K, V90Y, P681R
2	JN.1 variants with BA.2	14	V83F, L84K, P85L, F86L, N87I, D88V, V90L, Y170E, Q218L, T307Q, T333R, F456L, Q506P, P507T	2	P85L, V90Y
3	JN.1 variants with XBB	20	A83V, L84K, P85K, F86L, N87I, D88V, V90L, F92V, Y170E, Q218L, T315V, S316C, F318I, N331K, T333R, N334S, T346R, F456L, Q506P, P507T	3	A83F, V90Y, T346I