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. 2024 Jul 1;15:1376463. doi: 10.3389/fendo.2024.1376463

Table 1.

Weighted baseline characteristics of participants with NGM, prediabetes, and diabetes.

Total NGM Prediabetes Diabetes P value†
No. of participants 7739 4010 3192 537
Age, y, mean (SE) 47.23 (0.33) 42.66 (0.39) 51.58 (0.41) 61.29 (0.79) < 0.0001
Age, n (%) < 0.0001
 20–44 3443 (45.21) 2328 (56.92) 1049 (33.36) 66 (14.25)
 45–64 2756 (39.13) 1229 (34.00) 1323 (45.72) 204 (42.22)
 ≥ 65 1540 (15.66) 453 (9.07) 820 (20.91) 267 (43.54)
Sex, n (%) < 0.0001
 Male 3802 (48.76) 1704 (42.50) 1815 (57.03) 283 (50.97)
 Female 3937 (51.24) 2306 (57.50) 1377 (42.97) 254 (49.03)
Race, n (%) < 0.0001
 Non-Hispanic White 3863 (73.45) 1959 (72.35) 1615 (74.36) 289 (77.87)
 Non-Hispanic Black 1366 (8.64) 799 (9.90) 477 (6.98) 90 (8.17)
 Mexican American 1131 (7.35) 526 (6.85) 522 (8.03) 83 (7.41)
 Otder Race 1379 (10.55) 726 (10.89) 578 (10.62) 75 (6.55)
Education level, n (%) < 0.0001
 High school or less 3333 (35.80) 1503 (31.48) 1528 (39.96) 302 (48.68)
 Some college 2340 (31.46) 1292 (32.43) 911 (30.65) 137 (27.62)
 College graduate
 or above
2066 (32.75) 1215 (36.09) 753 (29.39) 98 (23.70)
Marital status, n (%) < 0.0001
 Divorced/
 Separated/Widowed
1533 (16.62) 682 (14.51) 679 (17.75) 172 (29.76)
 Married/Living witd
 a partner
4790 (66.40) 2362 (64.07) 2113 (70.23) 315 (61.60)
 Never married 1416 (16.98) 966 (21.42) 400 (12.02) 50 (8.64)
Poverty-to-income ratio, n (%) 0.11
 < 1.3 2207 (18.59) 1115 (18.53) 918 (18.03) 174 (23.28)
 1.3–3.5 2906 (35.76) 1480 (35.06) 1208 (36.36) 218 (38.46)
 > 3.5 2626 (45.65) 1415 (46.41) 1066 (45.61) 145 (38.26)
Glucose metabolism
 Fasting glucose, mg/dl 5.51 (0.01) 5.11 (0.01) 5.89 (0.01) 6.73 (0.05) < 0.0001
 2hPG, mg/dl 6.27 (0.04) 5.23 (0.03) 6.95 (0.05) 11.72 (0.16) < 0.0001
 HbA1c (%) 5.39 (0.01) 5.27 (0.01) 5.49 (0.01) 5.93 (0.03) < 0.0001
 HOMA−IR 2.91 (0.04) 2.12 (0.04) 3.65 (0.07) 5.43 (0.25) < 0.0001
Lipid metabolism
 Waist (cm) 97.98 (0.27) 93.61 (0.37) 102.82 (0.38) 106.79 (0.76)
 Total cholesterol, mg/dL 195.57 (0.68) 192.71 (0.85) 198.73 (1.05) 201.10 (2.26) < 0.0001
 HDL cholesterol, mg/dL 55.24 (0.25) 57.33 (0.33) 52.72 (0.40) 52.75 (0.91) < 0.0001
 LDL cholesterol, mg/dL 116.99 (0.55) 114.49 (0.72) 119.99 (0.87) 120.06 (2.16) < 0.0001
 Triglycerides, mg/dL 116.66 (1.09) 104.46 (1.09) 130.02 (1.98) 141.50 (2.98) < 0.0001
CVH scores 66.94 (0.33) 70.21 (0.39) 63.50 (0.45) 59.28 (0.66) < 0.0001
Healtd behaviors score 66.79 (0.45) 67.89 (0.56) 65.70 (0.60) 63.69 (0.87) < 0.001
 HEI-2015 diet score 39.24 (0.64) 39.32 (0.80) 39.08 (0.90) 39.68 (1.60) 0.95
 Physical activity score 72.84 (0.72) 76.16 (0.85) 70.03 (1.14) 59.99 (2.30) < 0.0001
 Nicotine exposure score 71.05 (0.78) 71.37 (1.04) 70.40 (0.91) 72.71 (1.95) 0.29
 Sleep healtd score 84.02 (0.45) 84.71 (0.55) 83.29 (0.62) 82.39 (1.26) 0.05
Healtd factors score 67.15 (0.35) 73.31 (0.45) 60.56 (0.50) 53.41 (1.15) < 0.0001
 Body mass index score 63.24 (0.53) 70.02 (0.73) 55.76 (0.82) 49.80 (1.58) < 0.0001
 Blood lipids score 65.09 (0.50) 69.88 (0.59) 59.79 (0.79) 55.70 (1.75) < 0.0001
 Blood pressure score 73.11 (0.50) 80.02 (0.66) 66.14 (0.77) 54.72 (1.66) < 0.0001

NGM, normal glucose metabolism; CVH, cardiovascular health; FPG, fasting plasma glucose; 2hPG, 2 h plasma glucose; HbA1c, hemoglobin A1C; HOMA-IR, homeostasis model assessment for insulin resistance; HEI, healthy eating index.

Data were presented as weighted percentages or means (95% confidence intervals).

†P for differences in baseline characteristics among participants with NGM, prediabetes, or diabetes.