Table 2.
Univariate Analysis Comparing Patients with and without CRP Normalisation.
| Patients without CRP normalisation | Patients with CRP normalisation | T-TEST/CHI2 | |
|---|---|---|---|
| Total | 59 | 35 | 94 |
| Male | 38 | 24 | 0.6 |
| Female | 21 | 11 | / |
| Median age | 63 | 61 | .45 |
| Median CCI | 4 | 3 | .31 |
| Bacteraemia | 44 | 25 | .73 |
| Frankel grade not E | 28 | 13 | .32 |
| Diabetes | 10 | 5 | .73 |
| Renal disease | 9 | 6 | .81 |
| Liver disease | 8 | 6 | .22 |
| Immunosuppression | 9 | 2 | .16 |
| IVDU | 3 | 6 | .054 |
| Median BMI (kg/m2) | 29 | 28 | 0.6 |
| ASA >1 | 53 | 26 | *0.04 |
| Thoracic disease | 27 | 8 | *0.02 |
| Multifocal sepsis | 41 | 13 | *0.002 |
| Conservative management only | 22 | 13 | .98 |
| Surgical management at any point | 37 | 22 | .98 |
| Converted to surgical management | 16 | 5 | .06 |
| >1 surgical debridement | 18 | 8 | .42 |
| Instrumentation | 5 | 5 | .36 |
| Bony involvement | 36 | 19 | .52 |
| S. aureus | 25 | 27 | *0.001 |
| Median length of stay (excluding patients who died in hospital) | 25 | 17.5 | *0.04 |
| Median pre-treatment Karnofsky Performance score | 90 | 90 | .12 |
| Median post-treatment Karnofsky Performance score | 70 | 90 | *0.03 |
| Pre-treatment Karnofsky score <80 | 19 | 6 | .11 |
| 30 Day mortality | 9 | 1 | *0.05 |
| 2 Year mortality | 16 | 2 | *0.01 |
Legend: * = Statistically significant, p =</= .05, CCI = Charlson Comorbidity Index, BMI = Body Mass Index, ASA = American Society of Anaesthesiologist Classification, IVDU= Intravenous Drug Use.