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. 2024 Jul 23;11(7):ENEURO.0165-24.2024. doi: 10.1523/ENEURO.0165-24.2024

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Copyright © 2024 Akter et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 5. — Characterization of gene expression in hiPSC-MNs at late mature stages. A, Venn diagram shows the RNAseq results of the number of genes that were only identified in late-stage iPSC-MNs at 21 dpi prepared with culture inserts. B, GO analysis of genes only expressed in iPSC-MNs at 21 dpi with the enrichment of terms related to neuron functions. C, Pathway enrichment analysis with KEGG and Reactome of genes only expressed in iPSC-MNs at 21 dpi. D, Representative genes involved in dendritogenesis are upregulated in iPSC-MNs at 21 dpi. E, Representative genes involved in synaptogenesis are upregulated in iPSC-MNs at 21 dpi. F, Representative genes involved in nucleocytoplasmic transport are upregulated in iPSC-MNs at 21 dpi.