Table 1. Characteristics of UK Biobank Participants Included in Analyses.
| Characteristic | No. with observed data | No. (%) or mean (SD) |
|---|---|---|
| Age, y | 304 953 | 62.06 (4.08) |
| Sex | 304 953 | |
| Female | 163 825 (53.72) | 163 825 (53.72) |
| Male | 141 128 (46.28) | 141 128 (46.28) |
| Primary cataracts-GRSa | 150 858 | 0.03 (0.98) |
| Myopia-GRSa | 150 858 | −0.02 (1) |
| AD-GRS with APOEa | 183 439 | 0.01 (1) |
| Self-reported cataracts | 304 953 | 14 295 (4.69) |
| Self-reported cataract surgery | 304 953 | 2335 (0.77) |
| Self-reported glaucoma | 304 953 | 6187 (2.03) |
| Self-reported AMD | 304 953 | 3321 (1.09) |
| Self-reported diabetic retinopathy | 304 953 | 2850 (0.93) |
| Myopia | 69 g3 | 19 670 (28.16) |
| Worse than 20/40 vision | 71 429 | 2754 (3.86) |
| Total brain volume, mm3 | 36 591 | 1 152 218.90 (109 824.54) |
| Lateral occipital volume, mm3 | 36 855 | 25 261.47 (3347.28) |
| Hippocampal volume, mm3 | 36 855 | 7998.23 (791.80) |
Abbreviations: AD, Alzheimer disease; AMD, age-related macular degeneration; APOE, apolipoprotein E; GRS, genetic risk score.
a
See Methods for explanation of scoring.