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. Author manuscript; available in PMC: 2024 Dec 7.
Published in final edited form as: Mol Cell. 2023 Nov 22;83(23):4205–4221.e9. doi: 10.1016/j.molcel.2023.10.037

Figure 5. Fpt1, embedded in the tDNA proteome, affects the RNAPIII transcription machinery.

Figure 5.

(A) Schematic outline: an FPT1 knockout strain is crossed with the WT Epi-Decoder library using SGA, resulting in an fpt1Δ Epi-Decoder library. The tDNA chromatin proteome of both libraries can be compared. (B) Fraction of proteins classified as ‘binder’ in fpt1Δ glucose or glycerol 2h (37°C) for different functional classes indicated (HSP refers to heat shock proteins). (C) Heat maps with average fold change values (ChIP vs input, n = 3) at the tDNA-Ty1 locus for different protein complexes or families for WT or fpt1Δ in glucose and 2h glycerol (37°C).