Table 1.
Doubling Time of DPCs.
| DP1 | DP31 | DP74 | DP165 | DP185 | DP264 | DP296 | ||
|---|---|---|---|---|---|---|---|---|
| Constant rate (k) | DPC-S | 0.445 | 0.458 | 0.315 | 0.331 | 0.260 | 0.435 | 0.405 |
| DPC-F | 0.548** | 0.588** | 0.144*** | 0.366 | 0.294 | 0.545*** | 0.541*** | |
| Doubling time (days) | DPC-S | 1.45 | 1.51 | 2.20 | 2.10 | 2.67 | 1.60 | 1.71 |
| DPC-F | 1.20 | 1.18 | 4.80 | 1.90 | 2.36 | 1.27 | 1.28 |
Effect of basic fibroblast growth factor (FGF2) priming on the growth of individual donor-derived clones (n = 7–8). The growth curves of individual dental pulp cell (DPC) clones were analyzed using nonlinear regression. The doubling times of DPC clones were calculated using ln (2)/k. **P < 0.001; ***P < 0.0001, the constant rate (k) was compared between DPC clones primed without and with the basic fibroblast growth factor (DPC-S and DPC-F, respectively), using the extra sum of the square F test.