Table 2.

Variables associated with vedolizumab withdrawal.

Variable	Univariable Cox regression			Multivariable Cox regression
	Hazard ratio	95% CI	p	Hazard ratio	95% CI	p
Disease extension
E1: distal (reference)			0.022			0.025
E2: left side	2.72	1.08–6.83	0.034	2.82	1.12–7.13	0.028
E3: extensive	2.94	1.19–7.23	0.019	3.40	1.37–8.42	0.008
Number of previous biologic/small molecule
None (reference)			0.004			0.007
One	1.53	1.05–2.22	0.028	1.54	1.05–2.25	0.028
Two or more	2.26	1.31–3.88	0.003	2.12	1.25–3.71	0.006
Concomitant steroids at baseline	1.67	1.16–2.42	0.006	1.54	1.05–2.27	0.027
Partial Mayo ⩾ 2 at baseline	1.81	1.11–2.94	0.017

CI, confidence interval.