Extended Data Fig. 3 |. Latent cells oxidize internalized FAs and maintain redox homeostasis.

a. Mass spectrometry data showing DRP1 post-translational modifications including Serine phosphorylation (S616) and Lysine K10, K92, K160, K238 and K597 acetylation peaks in HCC1954 Lat cells. b. Western blots showing expression of carnitine palmitoyl-transferase 1 A (CPT1A) in HCC1954 (upper panel) and SKBR3 (lower panel) Pa and Lat cells. c and d. ¹³C₁₆-Palmitic acid tracing showing enrichment of carnitine-conjugated fatty acids in HCC1954 and SKBR3 Pa and Lat cells. e-g. ¹³C₁₆-Palmitic acid tracing showing labeled isotopologues of citrate, glutamate, and malate in SKBR3 Pa and Lat cells. In c-g, ‘n’ represents biologically independent samples and data presented as mean + /−SEM. P values in c-g were calculated by two-tailed Unpaired t-test. The experiments shown in b was repeated independently three times with similar results.