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[Preprint]. 2024 Jul 24:2024.07.24.604946. [Version 1] doi: 10.1101/2024.07.24.604946

Figure 8. Average weight of wildtype and R6/2 mice across different timepoints.

Figure 8.

(A) Multiple comparisons of female mice; a = Wildtype vs Pv-Exc-hCTZ, p = 0.0236; b = Wildtype vs Emx-Inh-hCTZ, p = 0.0097; c = Emx-Inh-hCTZ vs Pv-Exc-hCTZ, p = 0.0106; d = Wildtype vs R6/2-untreated, p = 0.0420 and e = Wildtype vs Pv-Exc-hCTZ, p = 0.0171. (B) Multiple comparisons of male mice; a = Wildtype vs Emx-Inh-hCTZ, p = 0.0120; b = Wildtype vs Pv-Exc-hCTZ, p < 0.0019; c = Wildtype vs R6/2-untreated, p = 0.0001; d = Wildtype vs Emx-Inh-hCTZ, p = 0.0001; and e = Wildtype vs Pv-Exc-hCTZ, p < 0.0001. Significance was assessed by two-way ANOVA with Tukey’s post hoc comparison. All data are presented as the mean ± SEM (n = 5 – 10 mice/group).