Extended Data Fig. 4. Population stratification of eQTLs.

Geographic frequencies of autosomal lead eQTLs found in MAGE across (A) all lead eQTLs, (B) excluding variants with allele frequencies > 5% across all continental groups, (C) only including variants unobserved in the European continental group, and (D) only including variants unobserved in both the European and African continental groups. The geographic distributions are sorted with the most common at the bottom and rarest at the top. Allele frequencies are categorized as unobserved (U), rare variants with allele frequencies <5% (R), and common variants (C) with allele frequencies ≥5%.