TABLE 6.
Comparison of inflammatory marker levels from the baseline.
| Inflammatory markers | Day 0 | Day 90 | p-valuea | p-valueb |
|---|---|---|---|---|
| hs-CRP | ||||
| Placebo | 6.46 (3.64, 9.29) | 8.45 (6.69, 10.21) | 0.008 | |
| Boswellin (150 mg) | 9.29 (5.89,12.68) | 8.34 (6.22,10.48) | NS | NS |
| Boswellin (300 mg) | 11.90 (8.25,15.55) | 8.76 (5.87,11.66) | 0.018 | |
| TNF -Alpha | ||||
| Placebo | 56.88 (16.79, 96.96) | 57.94 28.61,87.27) | NS | |
| Boswellin (150 mg) | 38.05 (10.02,66.08) | 20.47 (8.86,32.08) | NS | NS |
| Boswellin (300 mg) | 40.15 (18.58,61.72) | 31.64 (5.64,57.65) | NS | |
| IL-6 | ||||
| Placebo | 30.86 (10.03, 51.68) | 52.16 (24.96,79.36) | 0.001 | |
| Boswellin (150 mg) | 50.67 (31.98,69.35) | 45.50 (24.82,66.18) | NS | NS |
| Boswellin (300 mg) | 43.94 (19.32,68.56) | 29.71 (10.51,48.91) | 0.015 | |
Mean and 95% Confidence interval of mean are given in the table, since the variation within groups was very high. hs-CRP- High sensitivity C reactive protein, TNF-α- Tumor necrosis factor, IL-6- Interleukin −6.
p valuea represents the difference between day 0 and day 90 within the group. p valueb represents the difference between the three groups in the change in biomarker levels.