Table 3.

Underlying disease/pathology and laboratory findings of participants.

	Overall (n = 212)	Obstetrical DIC (n = 10)	Control (n = 202)	P-value
New Japanese obstetrical DIC scores (points)	1 [0–9]	9 [8–9]	1 [0–7]	< 0.0001
I. Underlying disease/pathology (points)	0 [0–4]	4 [4–4]	0 [0–4]	< 0.0001
One or more (4 points)	25 (11.8%)	10 (100%)	15 (7.4%)	< 0.0001
Placental abruption	6 (2.8%)	2 (20.0%)	4 (2.0%)	0.0272
Amniotic fluid embolism	2 (0.94%)	2 (20.0%)	0 (0.0%)	0.0020
Postpartum hemorrhage non-clottable*	19 (9.0%)	8 (80.0%)	11 (5.5%)	< 0.0001
II. Coagulability finding (points)	0 [0–3]	3 [2–3]	0 [0–3]	< 0.0001
Fibrinogen < 150 mg/dL (3 points)	19 (9.0%)	9 (90.0%)	10 (5.0%)	< 0.0001
Fibrinogen ≥ 150– < 200 mg/dL (2 points)	13 (6.1%)	1 (10.0%)	12 (5.9%)	0.4765
Fibrinogen ≥ 200 to < 300 mg/dL (1 point)	55 (25.9%)	0 (0.0%)	55 (27.2%)	0.0668
III. Fibrinolysis finding (points)	0 [0–2]	2 [0–2]	0 [0–2]	< 0.0001
FDP ≥ 60 μg/mL or D-dimer ≥ 25 μg/mL (2 points)	34 (16.0%)	10 (100%)	24 (11.9%)	< 0.0001
FDP ≥ 30 μg/mL or D-dimer ≥ 15 μg/mL (1 point)	27 (12.7%)	0 (0.0%)	27 (13.4%)	0.3681
Previous Japanese obstetrical DIC score (points)	2 [0–33]	12 [8–33]	2 [0–16]	< 0.0001
≥ 8 points	30 (14.2%)	10 (100%)	20 (9.9%)	< 0.0001
Pregnancy-specific modified ISTH DIC score (points)	12 [0–52]	51 [26–52]	11 [0–52]	< 0.0001
≥ 26 points	82 (38.7%)	10 (100%)	72 (35.6%)	< 0.0001

*Postpartum hemorrhage (PPH) non-clottable was defined as massive PPH without blood clots.

DIC disseminated intravascular coagulation, FDP fibrin-fibrinogen degradation product, ISTH the International Society on Thrombosis and Hemostasis.