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. 2024 Jun 24;39(8):1673–1683. doi: 10.1093/humrep/deae127

Table 4.

Evolution of symptoms using a visual analogue scale—paired results.

HIFU (N = 58)
Mean ± SD (median) [IQR] (95% CI)
Gynaecological symptoms
 Acute pelvic pain/dysmenorrhoea
  Pre-op 6.2 ± 3.1 (7) [5; 8.3] (5.4; 7.0)
  Six months 2.8 ± 3.0 (2) [0; 5] (2.0; 3.6)
  Difference −3.4 ± 3.8 (−3) [−7; 0] (−4.4; −2.4)
  P-value <0.001
 Dyspareunia
  Pre-op 4.7 ± 3.3 (6) [0; 7.3] (3.8; 5.6)
  Six months 2.0 ± 2.9 (0) [0; 3.3] (1.3; 2.8)
  Difference −2.7 ± 3.3 (−3) [−5.3; 0] (−3.5; −1.8)
  P-value <0.001
Gastrointestinal symptoms
 Diarrhoea
  Pre-op 3.0 ± 3.3 (2.5) [0; 6] (2.2; 3.9)
  Six months 1.2 ± 2.3 (0) [0; 1.3] (0.6; 1.8)
  Difference −1.9 ± 3.1 (0) [−4; 0] (−2.7; −1.1)
  P-value <0.001
 Constipation
  Pre-op 4.7 ± 3.7 (5.5) [0; 8] (3.7; 5.7)
  Six months 2.2 ± 2.7 (0) [0; 4] (1.5; 2.9)
  Difference −2.5 ± 3.3 (−2) [−4; 0] (−3.4; −1.7)
  P-value <0.001
 Rectal bleeding
  Pre-op 1.1 ± 2.5 (0) [0; 0] (0.4; 1.7)
  Six months 0.4 ± 1.6 (0) [0; 0] (0.0; 0.9)
  Difference −0.6 ± 2.6 (0) [0; 0] (−1.3; 0.0)
  P-value 0.035
 False urges
  Pre-op 2.6 ± 3.0 (0) [0; 5] (1.8; 3.4)
  Six months 0.6 ± 1.9 (0) [0; 0] (0.2; 1.1)
  Difference −1.9 ± 2.8 (0) [−4; 0] (−2.7; −1.2)
  P-value <0.001
 Tenesmus/spasms
  Pre-op 5.7 ± 3.0 (6) [4.8; 8] (4.9; 6.5)
  Six months 2.8 ± 2.9 (3) [0; 5] (2.1; 3.6)
  Difference −2.8 ± 3.3 (−2.5) [−6; 0] (−3.7; −2.0)
  P-value <0.001
 Pain on defecation
  Pre-op 3.9 ± 3.7 (4) [0; 7] (2.9; 4.9)
  Six months 1.3 ± 2.1 (0) [0; 2.3] (0.8; 1.9)
  Difference −2.6 ± 3.1 (−2) [−5; 0] (−3.4; −1.7)
  P-value <0.001
General symptoms
 Post-pelvic pain
 Pre-op 3.6 ± 3.8 (3) [0; 7] (2.6; 4.6)
 Six months 2.1 ± 2.8 (0) [0; 3.3] (1.4; 2.8)
 Difference −1.5 ± 3.7 (0) [−5; 0] (−2.5; −0.5)
P-value 0.004
 Asthenia
 Pre-op 6.4 ± 2.6 (7) [5; 8] (5.7; 7.1)
 Six months 4.2 ± 3.0 (4) [1.8; 7] (3.5; 5.0)
 Difference −2.1 ± 3.1 (−2) [−4.3; 0] (−2.9; −1.3)
P-value <0.001

HIFU, high-intensity focused ultrasound; IQR, interquartile range.