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. 2024 Jul 31;10:135. doi: 10.1038/s41531-024-00745-8

Table 2.

AT(N) profiles of the participants

AT(N) profiles Low-risk (LR) High-risk (HR) PD DLB p values
LR vs HR LR vs PD LR vs DLB
A− T− (N)−, n (%) 19 (51.4) 30 (36.6) 25 (29.8) 0 (0.0) 0.192a 0.039 <0.001
A+ T− (N)−, n (%) 5 (13.5) 4 (4.9) 2 (2.4) 0 (0.0) 0.403a 0.164 0.614
A+ T+ (N)−, n (%) 1 (2.7) 0 (0.0) 1 (1.2) 0 (0.0) 1.000a 1.000 1.000
A+ T+ (N)+, n (%) 1 (2.7) 2 (2.4) 23 (27.4) 10 (62.5) 1.000a 0.002 <0.001
A+ T− (N)+, n (%) 1. (2.7) 5 (6.1) 1 (1.2) 2 (12.5) 0.664a 0.624 0.427
A− T+ (N)−, n (%) 3 (8.1) 2 (2.4) 5 (6.0) 0 (0.0) 1.000a 1.000 1.000
A− T− (N)+, n (%) 4 (10.8) 34 (41.5) 13 (15.5) 2 (12.5) 0.002a 0.873 1.000
A− T+ (N)+, n (%) 3 (8.1) 5 (6.1) 14 (16.7) 2 (12.5) 0.843a 0.640 0.843

Data represent value (%).

PD Parkinson’s disease, DLB Dementia with Lewy bodies.

A− Aβ composite < 0.376, A+ Aβ composite ≥ 0.376, T− log10 (p-tau181) < 0.374, T+ log10 (p-tau181) ≥ 0.374, N− log10 (NfL) < 1.65, N+ log10 (NfL) ≥ 1.65.

ap values determined by pairwise comparisons using Fisher’s exact test with Benjamini–Hochberg correction.